5-FU toxicity and nutritional deficiencies

Lead toxicity and nutritional deficiencies.

Under appropriate conditions, deficiencies of certain minerals and vitamins as well as high intakes of dietary fat increase the toxicity of a given dose of lead in experimental animals. The severity of lead poisoning can also be increased by the consumption of either deficient or excessive levels of protein. Mineral deficiencies appear to have some of the most profound effects on lead toxicity,...

5-FU schedules, serum 5-FU levels and their relationship to therapy response and toxicity in patients with gastrointestinal cancer.

Correspondence to Dr. Silke Cameron, MD Department of Gastroenterology and Endocrinology, University Medical Center Göttingen, Robert-Koch-Straße 40, 37075 Göttingen, Germany silke.cameron@med. uni-goettingen.de

DPYD variants to predict 5-FU toxicity: the ultimate proof.

5-FU-induced cardiac toxicity - an underestimated problem in radiooncology?

BACKGROUND 5-Fluorouracil (5-FU) is an antimetabolite, which is frequently used as chemotherapeutic agent for combined chemoradiotherapy. The purpose of this study was to present the clinical course of three patients who developed severe cardiac toxicity by 5-FU and to give a review of the literature on the cardiotoxic potential of 5-FU. RESULTS Cardiotoxicity is a rare, but relevant side eff...

Nutritional Deficiencies; Diagnosis and Treatment

The isolation in recent years of many vitamins in pure form and clinical tests of them have resulted in notable advances in our knowledge of their usefulness in clinical medicine. Dr. Youmans has been one of the pioneers in the study of this particular subject, and therefore is well qualified to write on it. As is evident from the title, as well as the preface, the body of information here gath...